Complicated Osteoporosis in Progeroid Syndrome: Treatment With Teriparatide

Teriparatide therapy is recommended for elderly men with low bone mineral density (BMD; T-score <−2.5) and at least 1 fragility fracture who are unable to tolerate bisphosphonates. We describe a 20-yr-old patient affected by PS and severe osteoporosis complicated with femoral fracture. The patient experienced a significant improvement in lumbar spine BMD after treatment with teriparatide.