A Simple Method for the Routine Detection of Somatic Quantitative Genetic Alterations in Colorectal Cancer

Conclusions: The somatic QMPSF is a simple method able to detect simultaneously on a routine basis several quantitative changes in tumors. Its flexibility will allow the integration of clinically relevant genes. This high throughput method should be a valuable complementary tool of fluorescent in situ hybrization and comparative genomic hybridization.