Keywords: از دست دادن هتروزیگوتیسم; Gynecological carcinosarcomas; germline mutations; BRCA1-related cancers; loss of heterozygosity; TP53 alterations;
مقالات ISI از دست دادن هتروزیگوتیسم (ترجمه نشده)
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Keywords: از دست دادن هتروزیگوتیسم; Cancer; Phytochemical; Radiotherapy; Radioprotection; Side effects; AP-1; activator protein-1; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CAPE; caffeic acid phenylethylester; CAT; chloramphenicol acetyltransferase; CBMN; cytokinesis block
Keywords: از دست دادن هتروزیگوتیسم; DNA damage repair; Genetics; Genomic copy number alterations; Loss of heterozygosity; Notch signaling pathway; Oral cancer; Segregation of chromosome; Squamous cell carcinoma; Telomere stability;
Keywords: از دست دادن هتروزیگوتیسم; Candida albicans; fluconazole; loss of heterozygosity; mating type-like gene;
Keywords: از دست دادن هتروزیگوتیسم; High-risk Western-type diet; Intestinal cancer; Energy metabolism; Loss of heterozygosity; PDK4; ERK; ApcMin/+ mice;
Keywords: از دست دادن هتروزیگوتیسم; Esophagus; Sequencing; Carcinogenesis; Driver Mutation; APOBEC; apolipoprotein B messenger RNA editing enzyme, catalytic polypeptide-like; CNA; copy number alteration; EAC; esophageal adenocarcinoma; ESCC; esophageal squamous cell carcinoma; ESSH; esophag
Keywords: از دست دادن هتروزیگوتیسم; BC; breast cancer; ER; oestrogen receptor; IDC; invasive ductal breast cancer; IHC; immunohistochemistry; GG; Genomic Grade; ILC; invasive lobular breast cancer; LOH; loss of heterozygosity; PR; progesterone receptor; RATHER; Rational Therapy for Breast C
Keywords: از دست دادن هتروزیگوتیسم; APC; adenomatous polyposis coli; AR; androgen receptor; CAFs; cancer-associated fibroblasts; CTL; cytotoxic T cells; EMT; epithelial-mesenchymal transition; EPCs; endothelial progenitor cells; FSP1; fibroblast specific protein 1; HNSCC; head and neck sq
Keywords: از دست دادن هتروزیگوتیسم; HSIL; high-grade squamous intraepithelial lesion; SCC; squamous cell carcinomas; CIN; cervical intraepithelial neoplasia; HPV; human papillomavirus; LOH; loss of heterozygosity; GEO; Gene Expression Omnibus; DEGs; differentially expressed genes; CDKN2A; I
Keywords: از دست دادن هتروزیگوتیسم; EcSOD; SOD3; Cancer; Reactive oxygen species; Heparin binding domain; Tumor suppressor; Metastasis; Recurrence; Relapse free survival; Epigenetic; Loss of heterozygosity; Single nucleotide polymorphism; microRNA-21; Oxidative tumor microenvironment;
Keywords: از دست دادن هتروزیگوتیسم; Meningioma; Loss of heterozygosity; LOH; Tumour recurrence;
Keywords: از دست دادن هتروزیگوتیسم; ALT; alanine aminotransferase; AST; aspartate transaminase; CA; carbohydrate antigen; CMP; cytidine monophosphate; CK; cytokeratin; DMB; dihydrochloride; EM; electromagnetic; FFPE; formalin-fixed, paraffin-embedded; GGC; Greenwood Genetic Center; GlcNAc;
Keywords: از دست دادن هتروزیگوتیسم; Meningioma; Loss of heterozygosity; Systematic review; Individual patient data; Meta-analysis;
Keywords: از دست دادن هتروزیگوتیسم; Melanoma; Liquid biopsy; Circulating tumor cells; Cell-free circulating tumor DNA; Cell-free DNA; Cell-free microRNA; Ab; antibody; AIM1; absent in melanoma-1; AJCC; American Joint Committee on Cancer; BRAF; B-Raf proto-oncogene, serine/threonine kinase;
Keywords: از دست دادن هتروزیگوتیسم; HSCR; Hirschsprung disease; CNV; copy number variation; LOH; loss of heterozygosity; qPCR; quantitative polymerase chain reaction; S-HSCR; short-segment Hirschsprung disease; L-HSCR; long-segment Hirschsprung disease; TCA; total colonic aganglionosis; SNP
Keywords: از دست دادن هتروزیگوتیسم; ASDs; Autism spectrum disorders; CNV; copy number variant; eIPSC; evoked IPSC; FMRP; fragile X mental retardation protein; FXS; fragile X syndrome; LOH; loss of heterozygosity; LTD; long-term depression; LTP; long-term potentiation; mEPSCs; miniature exci
Keywords: از دست دادن هتروزیگوتیسم; CAPRI; Ca2+-promoted RAS inactivator; CRMP-2; collapsin response mediator protein-2; CSRD; cysteine/serine-rich domain; CTD; C-terminal domain; ERK; extracellular signal-regulated kinase; FTI; farnesyltransferase inhibitor; FAK1; focal adhesion kinase 1;
Keywords: از دست دادن هتروزیگوتیسم; CRC; colorectal cancer; CTCs; circulating tumor cells; cfDNA; cell-free DNA; HMs; histon modifications; LOH; loss of heterozygosity; miRNAs; microRNAs; MSI; microsatellite instability; Colorectal cancer; Blood-based biomarkers; Liquid biopsy; Circulating
Keywords: از دست دادن هتروزیگوتیسم; Oral cancer; Squamous cell carcinoma; Japanese; Prevention; Proteomics; Metabolomics; Loss of heterozygosity; Copy number abnormality; Single nucleotide polymorphism; Comparative genomic hybridization
Keywords: از دست دادن هتروزیگوتیسم; Genomics; Chromosome Instability; Evolution; Overdiagnosis; BE; Barrett's esophagus; EA; esophageal adenocarcinoma; GWAS; genome-wide association studies; LOH; loss of heterozygosity; SNP; single nucleotide polymorphism;
Keywords: از دست دادن هتروزیگوتیسم; AChR; acetylcholine receptor; AChR-Ab; acetylcholine receptor antibody; AIRE; autoimmune regulator; APECED; autoimmune polyendocriopathy candidiasis ectodermal dystrophy; APS-I; autoimmune polyendocrine syndrome type-I; EOMG; early onset Myasthenia gravis
Keywords: از دست دادن هتروزیگوتیسم; Melanoma; Uveal; Cytogenetic; Multiplex ligation probe amplification; Microsatellite analysis; Loss of heterozygosity; Melanoma; Uveal; Citogenético; Multiplex-ligation-prove amplification; Análisis de microsatélites; Pérdida de heterocigosidad;
Keywords: از دست دادن هتروزیگوتیسم; LOH; loss of heterozygosity; NGS; next-generation sequencing; SNP-RFLP; single nucleotide polymorphism-restriction fragment length polymorphism; INDEL; INsertion/DELetion; CAHCA; Comparative Allele Haplotyping for C. albicans; RDmean; mean depth of reads;
Keywords: از دست دادن هتروزیگوتیسم; polycystic liver disease; loss of heterozygosity; hepatobiliary organogenesis; ductal plate malformation; hepatic cystogenesis; primary cilium
Keywords: از دست دادن هتروزیگوتیسم; ccRCC; clear cell renal cell carcinoma; FHIT; fragile histidine triad; HWE; Hardy-Weinberg equilibrium; LOH; loss of heterozygosity; MGB; minor groove binder; OR; odds ratio; PFS; progression-free survival; PTPRD; protein tyrosine phosphatase receptor t
Keywords: از دست دادن هتروزیگوتیسم; Oral cancer; Premalignant oral lesions; Leukoplakia; Loss of heterozygosity; p53; Malignant transformation; Molecular diagnosis; Screening;
Keywords: از دست دادن هتروزیگوتیسم; HCC; hepatocellular carcinoma; IM; intrahepatic metastasis; LOH; loss of heterozygosity; MO; multicentric occurrence; PCR; polymerase chain reaction; RHCC; recurrent hepatocellular carcinoma;
Keywords: از دست دادن هتروزیگوتیسم; BM; basement membrane; ECM; extracellular membrane; EMT; epithelial mesenchymal transition; FAK; focal adhesion kinase; MAPK; mitogen-activated protein kinase; LOH; loss of heterozygosity; NCOR1; nuclear receptor co-repressor 1; MMP; matrix metalloprotein
The function and clinical significance of eIF3 in cancer
Keywords: از دست دادن هتروزیگوتیسم; eIFs; eukaryotic translation initiation factors; eIF3; eukaryotic translation initiation factor 3; IRES; internal ribosome entry site; PABP; polyA binding protein; CKIs; cyclin-dependent kinase inhibitors; NER; nucleotide excision repair; GC; gastric carc
Circulating histocompatibility antigen (HLA) gene products may help differentiate benign from malignant indeterminate pulmonary lesions
Keywords: از دست دادن هتروزیگوتیسم; NSCLC; non-small cell lung cancer; HLA; human leukocyte antigens; LDCT; low-dose computed tomography; MHC; major histocompatibility complex; ATCC; American Type Culture Collection; RPMI; Roswell Park Memorial Park; SDS-PAGE; standard denaturing polyacryla
Value of 18F-FET PET in adult brainstem glioma
Keywords: از دست دادن هتروزیگوتیسم; ADC; apparent diffusion coefficient; BSG; brain stem glioma; Cho; choline; CT; computed tomography; DTI; diffusion tensor imaging; DWI; diffusion weighted imaging; FET; 18F-fluoro-ethyl-tyrosine; FLAIR; fluid-attenuated inversion recovery; GBM; glioblasto
Dual BRD4 and AURKA Inhibition Is Synergistic against MYCN-Amplified and Nonamplified Neuroblastoma
Keywords: از دست دادن هتروزیگوتیسم; AURKA; aurora kinase A; BRD4; Bromodomain-containing protein 4; CI; combination index; Fa; fraction affected; p-AURKA; phosphorylated AURKA, specifically at threonine 288; LOH; loss of heterozygosity; 11q; long arm of chromosome 11;
Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation
Keywords: از دست دادن هتروزیگوتیسم; DA; dominant active; DN; dominant negative; DCIS; ductal carcinoma in situ; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ERK; extracellular-signal regulated kinase; ER; estrogen receptor; GAP; GTPase activating protein; GFP; green
Identification of biparental and diploid blastocysts from monopronuclear zygotes with the use of a single-nucleotide polymorphism array
Keywords: از دست دادن هتروزیگوتیسم; Loss of heterozygosity; monopronuclear zygote; preimplantation genetic screening; uniparental; single-nucleotide polymorphism;
Nuclear BAP1 loss is common in intrahepatic cholangiocarcinoma and a subtype of hepatocellular carcinoma but rare in pancreatic ductal adenocarcinoma
Keywords: از دست دادن هتروزیگوتیسم; BAP1; Loss of heterozygosity; 3p21 region; Liver cancer; Pancreatic cancer;
Whole-Exome Sequencing of Acquired Nevi Identifies Mechanisms for Development and Maintenance of Benign Neoplasms
Keywords: از دست دادن هتروزیگوتیسم; CNA; copy number aberration; LOH; loss of heterozygosity; SNV; single-nucleotide variants; TCGA; The Cancer Genome Atlas;
Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer
Keywords: از دست دادن هتروزیگوتیسم; Colon Cancer; Familial Colorectal Cancer; Protein Translation; Mechanism; CRC; colorectal cancer; LOH; loss of heterozygosity; MAF; minor allele frequency; miRNA; microRNA; MMR; DNA mismatch repair; PBS; phosphate-buffered saline; PCR; polymerase chain re
Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells
Keywords: از دست دادن هتروزیگوتیسم; Apoptosis; Cell death; Noxa; TAp73; EGR1; GANT61; Hedgehog signaling; Rhabdomyosarcoma; Medulloblastoma; ARMS; alveolar RMS; CNS; central nervous system; DSMZ; Deutsche Sammlung von Mikroorganismen und Zellkulturen; EGR1; early growth response protein 1;
Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation
Keywords: از دست دادن هتروزیگوتیسم; TSC; Tuberous Sclerosis Complex; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; LOH; loss of heterozygosity; iPSCs; induced pluripotent stem cells; NPCs; neural progenitor cells; PI3K; phosphoinositide 3-kinase; SENs; subependymal nodules; S
Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits
Keywords: از دست دادن هتروزیگوتیسم; BRCA1; BRCA2; Methylation; Loss of heterozygosity; Tumor cell percentage;
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: از دست دادن هتروزیگوتیسم; AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
Emerging paradigms in the treatment of liver metastases in colorectal cancer
Keywords: از دست دادن هتروزیگوتیسم; CRC; colorectal cancer; mCRC; metastatic colorectal cancer; CLM; colorectal liver metastases; SR; surgical resection; PVE; portal vein embolism; RFA; radiofrequency ablation; APC; adenomatous polyposis coli; LOH; loss of heterozygosity; EGFR; epidermal gr
Breeding of a non-urea-producing sake yeast carrying a FAS2 mutation
Keywords: از دست دادن هتروزیگوتیسم; Arginase; CAR1; Ethyl caproate; Ethyl carbamate; Loss of heterozygosity;
Case reportPneumothorax caused by cystic and nodular lung metastases from a malignant uterine perivascular epithelioid cell tumor (PEComa)
Keywords: از دست دادن هتروزیگوتیسم; Cystic lung disease; Loss of heterozygosity; Multiple lung nodules; PEComa; Pneumothorax; Pulmonary metastasis; CAPUs; clinically aggressive PEComas of the uterine corpus; CT; computed tomography; ESS; endometrial stromal sarcoma; GnRH; gonadotropin-relea
Genome instabilities arising from ribonucleotides in DNA
Keywords: از دست دادن هتروزیگوتیسم; AGS; Aicardi Goutieres Syndrome; DSB; double-strand break; HR; homologous recombination; Top1; topoisomerase 1; LOH; loss of heterozygosity; ncRNA; non-coding RNA; RER; ribonucleotide excision repair; dNTP; deoxynucleotide triphosphate; rNTP; ribonucleoti
Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence
Keywords: از دست دادن هتروزیگوتیسم; OSCC; oral cavity squamous cell carcinoma; FISH; fluorescence in situ hybridization; CI; chromosomal instable neoplasia; CIS; carcinoma in situ; LOH; loss of heterozygosity; MPTC; Maastricht Pathology Tissue Collection Department; CNV; copy number variati
MTUS1, a gene encoding angiotensin-II type 2 (AT2) receptor-interacting proteins, in health and disease, with special emphasis on its role in carcinogenesis
Keywords: از دست دادن هتروزیگوتیسم; Ang II; angiotensin II; ATIP; angiotensin II (AT2) receptor-interacting protein; AT2; angiotensin II receptor type 2; BTCC; bladder transitional cell carcinoma; CNV; copy number variant; ERK; extracellular-regulated kinase; ESCC; esophageal squamous cell
Detection of genetic alterations in cfDNA as a possible strategy to monitor the neoplastic progression of Barrett's esophagus
Keywords: از دست دادن هتروزیگوتیسم; APC; argon plasma coagulation; BE; Barrett's esophagus; BM; Barrett's metaplasia; cfDNA; cell-free DNA; EAC; esophageal adenocarcinoma; FAL; fractional allelic loss; HGD; high-grade dysplasia; LGD; low-grade dysplasia; LOH; loss of heterozygosity; MS; mic
Mutation Profile and Fluorescence In Situ Hybridization Analyses Increase Detection of Malignancies in Biliary Strictures
Keywords: از دست دادن هتروزیگوتیسم; ERCP; Cancer Detection; Mutation Profile; Diagnosis; CEP; chromosome enumeration probed; ERCP; endoscopic retrograde cholangiopancreatography; FISH; fluorescence in situ hybridization; LOH; loss of heterozygosity; MP; DNA mutation profiling; PCR; polymera
Sirolimus Therapy for Patients With Lymphangioleiomyomatosis Leads to Loss of Chylous Ascites and Circulating LAM Cells
Keywords: از دست دادن هتروزیگوتیسم; LAM; lymphangioleiomyomatosis; LOH; loss of heterozygosity; TPN; total parenteral nutrition; TSC; tuberous sclerosis complex; VEGF-D; vascular endothelial growth factor D;