کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3328891 1212358 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Curcumin for monoclonal gammopathies. What can we hope for, what should we fear?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Curcumin for monoclonal gammopathies. What can we hope for, what should we fear?
چکیده انگلیسی

Over the last decades there has been an increasing interest in a possible role of curcumin on cancer. Although curcumin is considered safe for healthy people, conclusive evidence on the safety and efficacy of curcumin for patients with monoclonal gammopathies is, so far, lacking. The present paper reviews the literature on molecular, cellular and clinical effects of curcumin in an attempt to identify, reasons for optimism but also for concern. The results of this critical evaluation can be useful for both patient- selection and monitoring in the context of clinical trials. Curcumin might be helpful for some but certainly not for all patients with monoclonal gammopathies. It is important to avoid unnecessary detrimental side effects in some in order to safeguard curcumin for those that could benefit. Parameters for patient monitoring, that can be used as early warning signs and as indicators of a favorable development have therefore been suggested.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 84, Issue 3, December 2012, Pages 350–360
نویسندگان
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