کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3329764 1212418 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quality of life beyond 6 months after diagnosis in older adults with acute myeloid leukemia
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Quality of life beyond 6 months after diagnosis in older adults with acute myeloid leukemia
چکیده انگلیسی

Although intensive chemotherapy may improve survival in older people with acute myeloid leukemia (AML) without adverse cytogenetics, its impact on quality of life (QOL) is mixed and most patients complain of fatigue up to 6 months after diagnosis. Little information is available on longer-term QOL outcomes. We prospectively followed 20 patients age 60 or older with AML who provided QOL data more than 6 months after diagnosis. Over the first 6 months, there were clinically important improvements in global health, role function, social function, and emotional function. Physical function and cognitive function were stable over time. Over the next 6 months, social function and fatigue improved, and other domains remained stable. Achievement of complete remission appeared to be associated with improvements in global health, physical function, and role function without negatively affecting other health domains. This information may aid discussions with patients about treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 69, Issue 2, February 2009, Pages 168–174
نویسندگان
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