کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3330065 1212429 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cancer vaccines: Accomplishments and challenges
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Cancer vaccines: Accomplishments and challenges
چکیده انگلیسی

Advancements in knowledge in diverse fields of science, including genetics, cell biology, molecular biology and biochemistry, have shed light on the origins of cancer and cell intrinsic properties that allow it to grow, invade and metastasize. Many therapies currently in use or under development are based on this knowledge. Advances in immunology, on the other hand, have shed light on how the host responds to these malignant properties of cancer. Based on that knowledge, immunotherapy, in particular vaccines directed at improving the host response against cancer, is being developed as an alternative therapeutic approach. In this review, we address main issues that have driven development of cancer vaccines and the challenges that have been met and/or are anticipated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 67, Issue 2, August 2008, Pages 93–102
نویسندگان
, ,