کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3330226 1212441 2007 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults
چکیده انگلیسی

Although intensive chemotherapy (IC) may modestly improve survival compared to supportive care in older people with acute myeloid leukemia (AML), treatment may worsen quality of life (QOL) and functional status. We assessed QOL and functional status at baseline, 1 month, 4 months, and 6 months in 65 consecutive, English-speaking, patients age 60 or older with newly diagnosed AML. At baseline, functional status was high but QOL was negatively affected in global health and most QOL domains. Over time, QOL remained stable or improved in most patients and was generally similar between IC and non-IC groups. Basic activities of daily living (ADL) scores did not change over time, whereas instrumental ADL scores declined slightly regardless of treatment. Receiving IC does not appear to lead to worse QOL or functional status than more palliative approaches. This information may aid treatment discussions in older patients with AML.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 64, Issue 1, October 2007, Pages 19–30
نویسندگان
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