Détection et valeur pronostique de la maladie minime médullaire et sanguine au diagnostic des rhabdomyosarcomes alvéolaires : étude rétrospective de la société française de lutte contre les cancers et des leucémies de l'enfant et de l'adolescent

With all the limitation of a retrospective analysis - and despite the limited number of patients - this is the first study to examine the pejorative prognostic value of the presence of bone marrow or blood micrometastasis at diagnosis in children with aRMS. It is the first step leading to a large-scale on going prospective study to confirm this assumption. If this is confirm in a larger setting, this would classify patients with bone marrow or blood micrometastasis in a high-risk population, to be treated more intensively or with new therapeutic strategies.