کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3335744 1213542 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Risk factors for adverse events during collection of peripheral blood stem cells
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Risk factors for adverse events during collection of peripheral blood stem cells
چکیده انگلیسی
We retrospectively reviewed peripheral blood stem cell (PBSCs) collections following 528 mobilization cycles over a 10-year period. A total of 206 (13.1%) AEs occurred in association with the 1572 procedures. One hundred and ninety-one (12.15%) of the AEs were classified as clinical AEs and 15 (0.95%) were classified as apheresis instrument related AEs. The most common clinical AE was numbness of the lips, tongue, or extremities (161 procedures, 10.2%) related to the infusion of acid citrate dextrose-A (ACD). Multivariate analysis revealed high amounts of ACD/weight (odds ratio [OR] = 1.11, p = 0.009), high numbers of procedures (OR = 1.33, p < 0.001) and female gender (OR = 2.83, p < 0.001) as being significantly associated with clinical AEs. Female gender was shown to be the most important risk factor for clinical AEs. Females who have a significantly increased risk of AEs would benefit from prophylactic calcium before and/or during PBSC collection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 45, Issue 1, August 2011, Pages 13-16
نویسندگان
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