کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3336419 | 1213574 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effect of cromoglycate on time-dependent histamine and serotonin concentrations in stored blood products
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
هماتولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The effect of cromoglycate on time-dependent histamine and serotonin concentrations in stored blood products The effect of cromoglycate on time-dependent histamine and serotonin concentrations in stored blood products](/preview/png/3336419.png)
چکیده انگلیسی
Biogenic amines, having vascular and inflammatory effects, are accepted as a potential threat for some non-hemolytic transfusion reactions. The aim of this study was to investigate time-dependent histamine/serotonin levels in stored blood products and to see whether cromoglycate has any effect on these mediators. Either for platelet or whole blood, 10-fold concentrations of cromoglycate (1 μg mlâ1, 10 μg mlâ1, 100 μg mlâ1) with controls prepared as pairs of replicate bags collected from two healthy subjects, separately. By using enzyme immunoassay, histamine and serotonin levels were determined in platelet or blood replicates. Histamine levels increased significantly with time but serotonin remained unchanged during the storage of platelet or blood specimens. Cromoglycate had no effect on these biogenic amines except an increase of serotonin in whole blood specimens containing 100 μg mlâ1 of it. So, cromoglycate cannot protect blood products against rising levels of histamine or serotonin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 34, Issue 2, April 2006, Pages 193-198
Journal: Transfusion and Apheresis Science - Volume 34, Issue 2, April 2006, Pages 193-198
نویسندگان
Kamuran Konca, E. Naci Tiftik, Gönül Aslan, Arzu Kanık, Atilla Yalçın,