کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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334260 | 546034 | 2009 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Substance use in severe mental illness: self-medication and vulnerability factors Substance use in severe mental illness: self-medication and vulnerability factors](/preview/png/334260.png)
The aim of this article is to examine the onset and clinical correlates of substance use in patients with psychotic disorders. One hundred and eight inpatients and outpatients with DSM-IV psychotic disorders were evaluated with the SCI-SUBS, an instrument designed to explore the spectrum of substance use and its clinical correlates. Comparisons were made between subjects with (n = 47) and without (n = 61) a DSM-IV diagnosis of substance use disorder (SUD). In patients with an early onset of psychosis (< 17 years), the onset of SUD was subsequent. Patients with SUD had higher substance sensitivity, higher sensation-seeking traits and were more likely to self-medicate than patients without SUD. The reasons for self-medication endorsed by patients with SUD included relieving depression, achieving or maintaining euphoria, improving self-confidence and social abilities. Our results, based on a cross-sectional study, suggest that early onset of psychosis, substance sensitivity and sensation-seeking traits represent vulnerability factors for SUD. The relationships between SUD and psychosis should be examined systematically and clarified in longitudinal studies.
Journal: Psychiatry Research - Volume 165, Issues 1–2, 30 January 2009, Pages 88–95