کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3344679 | 1591223 | 2006 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Vaccine therapy of malignant melanoma
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Malignant melanoma is a lethal disease for which the only curative therapy of proven benefit is complete surgical resection for early stage disease. Melanoma is a disease that is usually resistant to systemic therapy, with dacarbazine and interleukin-2 being the only 2 United States Food and Drug Administration approved drugs for advanced disease, and interferon alfa-2b the only one approved therapy for adjuvant treatment of high-risk disease. Evidence has shown that melanoma cells can be immunogenic prompting extensive basic and clinical research attempting to develop effective antimelanoma vaccine therapies. In this review, we concentrate on clinical results of vaccine trials in patients with melanoma.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical and Applied Immunology Reviews - Volume 6, Issues 3–4, May–August 2006, Pages 217–230
Journal: Clinical and Applied Immunology Reviews - Volume 6, Issues 3–4, May–August 2006, Pages 217–230
نویسندگان
Daniel Farray, Joseph I. Clark,