Allergic rhinitis and asthma: celebrating 100 years of immunotherapy

Since Noon first described allergen immunotherapy a century ago the basic premise of subcutaneous injections (SCIT) of relevant aeroallergens to induce clinical tolerance has remained true [1]. Indeed, allergen immunotherapy did not change dramatically over the first 75 years, but over the past 25 years there have been a number of important advancements leading to newer approaches and novel formulations. Here we review the top 50 articles published in the past 2 years on allergens, environmental control, and immunotherapy for asthma and allergic rhinitis and the use of immunomodulators in allergic disease.

► Review top articles in past 2 years on immunotherapy for allergic rhinitis, asthma.
► Review recent significant articles on allergens and allergen avoidance.
► Review current articles relating to adverse events associated with immunotherapy.
► Review top articles on omalizumab.