کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3356120 1591582 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Are dendritic cells central to regulatory T cell function?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Are dendritic cells central to regulatory T cell function?
چکیده انگلیسی

The role of dendritic cells (DCs) as sentinels and inducers of immunity has been amply documented in the past 35 years. More recently, experimental evidence has suggested that DCs may also be critical to maintain tolerance to self-antigens. These opposing functions are complementary and would ensure the integrity of the organism in an environment full of pathogens. In this review, we summarize the observations supporting the hypothesis that DCs induce and maintain tolerance by a mechanism involving regulatory T cells.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 119, Issues 1–2, 15 August 2008, Pages 12–16
نویسندگان
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