کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3368986 1218993 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cerebral vasculitis and encephalitis due to Epstein–Barr virus in a patient with newly diagnosed HIV infection
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Cerebral vasculitis and encephalitis due to Epstein–Barr virus in a patient with newly diagnosed HIV infection
چکیده انگلیسی

Epstein–Barr virus (EBV) is a common infection which usually produces mild or no symptoms in immunocompetent individuals. In human immunodeficiency virus (HIV) associated immunosuppression it is most commonly associated with malignancy which usually occurs at very low CD4+ cell counts. We describe a newly diagnosed HIV-positive patient who presented with headaches and cerebellar signs. She was incorrectly diagnosed with cerebral tuberculosis (TB) infection based on the histology report from a cerebellar biopsy specimen. After extensive investigation including cerebrospinal fluid sampling and reanalysis of the brain biopsy specimens she was found to have EBV-associated cerebral vasculitis and encephalitis and was successfully treated with valganciclovir and steroids. Whilst there are a few reports of EBV-associated encephalitis, cerebral vasculitis secondary to EBV in the context of HIV infection has not previously been described in the literature.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Virology - Volume 59, Issue 4, April 2014, Pages 264–267
نویسندگان
, ,