کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3391526 | 1221056 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
External influences on the immune system via activation of the aryl hydrocarbon receptor
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
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چکیده انگلیسی
The aryl hydrocarbon receptor (AhR), subject of intensive research over three decades by the pharmacology/toxicology field has recently made its entry into mainstream immunology research and is set to continue to intrigue with ever more complex modes of modulating immune responses. The discovery of high and selective AhR expression on Th17 cells [1–3] and its role in induction of the cytokine IL-22 [1] attributed new immunological functions to this transcription factor and stimulated further research into physiological functions of the AhR in the immune system. A number of recent reviews [4–11] have highlighted potential new avenues of research. This review addresses recent new insight into physiological roles of AhR in the immune system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Immunology - Volume 23, Issue 2, April 2011, Pages 99–105
Journal: Seminars in Immunology - Volume 23, Issue 2, April 2011, Pages 99–105
نویسندگان
Brigitta Stockinger, Keiji Hirota, Joao Duarte, Marc Veldhoen,