کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3394703 | 1221485 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prediction of Plasmodium falciparum placental infection according to the time of infection during pregnancy
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کلمات کلیدی
ROCiPTPAUC - AUCPrevention strategy - استراتژی پیشگیریPregnancy - بارداریROC analysis - تجزیه و تحلیل ROCSulfadoxine-pyrimethamine - سولفادوکسین-پیریمتیامینPlacental infection - عفونت واژنMalaria - مالاریاarea under the curve - منطقه تحت منحنیreceiver operating characteristics - ویژگی های عملکرد گیرنده
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
انگل شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Malarial infection during pregnancy leads to placental infection, a known risk factor for low birth weight. Whether the stage of pregnancy at infection has a differential influence on these effects is not clearly known, but may be of importance for prevention strategies, including intermittent preventive treatment of pregnant women. Malaria infection during early (before 20 weeks), middle (20-28 weeks), or late (after 28 weeks) pregnancy was evaluated by logistic regression and receiver operating characteristics analysis in relation to placental infection in pregnant Senegalese women. Plasmodium falciparum infections during late pregnancy are strongly related to placental infection, as well as those that occur in middle pregnancy. Knowledge of parasitological events over the entire duration of pregnancy permits a highly accurate prediction of placental infection. Not only malaria infections during late pregnancy increase the likelihood of placental infection. The current policy of intermittent preventive treatment of pregnant women, which implies an initial antimalarial cure after 20 weeks of pregnancy, will not avoid early infections. An earlier initiation of malaria prevention might improve its efficacy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 98, Issue 3, July 2006, Pages 255-260
Journal: Acta Tropica - Volume 98, Issue 3, July 2006, Pages 255-260
نویسندگان
Gilles Cottrell, Philippe Deloron, Nadine Fievet, Sokhna Sow, Oumar Gaye, Jean-Yves Le Hesran,