کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3397532 | 1222232 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Clinical impact of a highly prevalent Pseudomonas aeruginosa clone in Dutch cystic fibrosis patients
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
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چکیده انگلیسی
Studies suggest that infection with highly prevalent Pseudomonas aeruginosa clones in cystic fibrosis (CF) is associated with an unfavourable clinical outcome. We studied the clinical characteristics of patients infected with a recently described, highly prevalent P. aeruginosa clone (ST406) in two CF centres in The Netherlands. Multilocus sequence typing data were available for 219 patients, of whom 40 (18.3%) were infected with ST406 and 179 with other sequence types. ST406 infection was independently associated with age, having a sibling with ST406 infection and use of inhaled antibiotics, but not with unfavourable clinical outcome, suggesting that high transmissibility is not necessarily associated with high virulence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 17, Issue 3, March 2011, Pages 382–385
Journal: Clinical Microbiology and Infection - Volume 17, Issue 3, March 2011, Pages 382–385
نویسندگان
A.M.M. de Vrankrijker, R.W. Brimicombe, T.F.W. Wolfs, H.G.M. Heijerman, R. van Mansfeld, F.T. van Berkhout, R.J.L. Willems, M.J.M. Bonten, C. K. van der Ent,