کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3397812 1222250 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adaptive drug resistance mediated by root–nodulation–cell division efflux pumps
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Adaptive drug resistance mediated by root–nodulation–cell division efflux pumps
چکیده انگلیسی

Bacterial resistance to antibiotics is a major therapeutic problem. Bacteria use the same mechanisms for developing resistance to antibiotics as they do for developing resistance to biocide compounds present in some cleaning and personal care products. Root–nodulation–cell division (RND) family efflux pumps are a common means of multidrug resistance, and induction of their expression can explain the observed cross-resistance found between antibiotics and biocides in laboratory strains. Hence, there is a relationship between the active chemicals used in household products, organic solvents and antibiotics. The widespread use of biocide-containing modern-day household products may promote the development of microbial resistance and, in particular, cross-resistance to antibiotics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 15, Supplement 1, January 2009, Pages 32–36
نویسندگان
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