کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3403218 | 1222770 | 2006 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
EtiologÃa y patogenia de las hepatitis vÃricas
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
In the strictest sense, the term “viral hepatitis” includes a series of clinical conditions of infectious origin caused by five phylogenetically unrelated human viruses that have developed specific tropism to hepatocytes. In a broader sense, it also includes acute liver diseases due to infection by other viruses that do not display specific liver tropism, but may produce liver disease as a complication of the infection. Hepatitis B and C viruses have, in addition, developed strategies that allow them to establish long-lasting, chronic infections in some patients. Chronic viral hepatitis, liver cirrhosis and primary liver cancer are the main clinical outcomes of these phenomena of viral persistence, which respond to two main mechanisms: induction of immune tolerance in the host, and emergence and selection of viral mutants that are able to escape the immune response.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Enfermedades Infecciosas y MicrobiologÃa ClÃnica - Volume 24, Issue 1, January 2006, Pages 45-56
Journal: Enfermedades Infecciosas y MicrobiologÃa ClÃnica - Volume 24, Issue 1, January 2006, Pages 45-56
نویسندگان
José Manuel EchevarrÃa-Mayo,