کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
340403 548227 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spatial working memory deficits in adolescents at clinical high risk for schizophrenia
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Spatial working memory deficits in adolescents at clinical high risk for schizophrenia
چکیده انگلیسی

Identifying endophenotypic markers is crucial to schizophrenia research for finding appropriate preventive strategies. Working memory (WM) deficit has been suggested as a marker for schizophrenia but its presence in adolescents at high risk is understudied. We piloted a test of spatial WM function in adolescents at clinical high risk (CHR) for schizophrenia and in age- and IQ-matched low-risk control subjects. CHR adolescents showed deficits in spatial WM compared with controls but showed intact performance on a non-WM-demanding spatial control task. Although based on a small pilot study, the results strongly suggest that WM deficit may be a risk factor for psychosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Schizophrenia Research - Volume 81, Issues 2–3, 31 January 2006, Pages 211–215
نویسندگان
, , ,