کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3414754 1224892 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Association between polymorphisms in OAS2 and CD209 genes and predisposition to chronic hepatitis C in Russian population
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Association between polymorphisms in OAS2 and CD209 genes and predisposition to chronic hepatitis C in Russian population
چکیده انگلیسی

Chronic hepatitis C is a severe liver disease caused by positive-strand RNA virus. Previously, we reported an association between seven single nucleotide polymorphisms (SNPs) in four innate immunity genes (OAS2, OAS3, CD209, and TLR3) and human predisposition to tick-borne encephalitis, caused by a virus from the same Flaviviridae family, in a Russian population. Currently, genotype and allele frequencies for these SNPs were analyzed in 75 chronic hepatitis C patients and compared with the population control (269 Novosibirsk citizens). Data obtained suggest that the OAS2 rs1293762 and CD209 rs2287886 SNPs are associated with predisposition to chronic hepatitis C in Russian population.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbes and Infection - Volume 16, Issue 5, May 2014, Pages 445–449
نویسندگان
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