کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3415192 | 1593650 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Experimental infection of cats with Bartonella henselae resulted in rapid clearance associated with T helper 1 immune responses
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Six cats were inoculated with Bartonella henselae strains A and B, which were isolated from the same naturally infected cat. The numbers of CD4+ cells decreased following the infection. The levels of bacteremia were significantly correlated with the expression levels of IFN-γ mRNA during the various stages of bacteremia and elimination of the bacteremia. Furthermore, the lower levels of TNF-α mRNA expression during the bacteremia related to the emergence of higher levels of bacteremia. These results indicate that the activation of cell-mediated immune responses, including IFN-γ and TNF-α production, play an important role in elimination of B. henselae from bacteremic cats.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbes and Infection - Volume 11, Issues 6–7, May–June 2009, Pages 716–720
Journal: Microbes and Infection - Volume 11, Issues 6–7, May–June 2009, Pages 716–720
نویسندگان
Hidenori Kabeya, Tamao Umehara, Hiroki Okanishi, Izumi Tasaki, Misako Kamiya, Akihiro Misawa, Takeshi Mikami, Soichi Maruyama,