کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3424859 | 1227253 | 2010 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Prevalence and stability of antibodies to 37 human papillomavirus types — A population-based longitudinal study Prevalence and stability of antibodies to 37 human papillomavirus types — A population-based longitudinal study](/preview/png/3424859.png)
Information about serostability of cutaneous HPV types over time is very limited. We investigated seroprevalence and serostability of 37 different HPV types over 4½ years in an Australian population-based study. Sera and data were analyzed for 390 people who had never been diagnosed with SCC and had blood collected in 1992, 1993 and 1996.Eighty-six percent of participants were seropositive to at least one of the 37 HPV types at baseline. HPV-4 was the type with the highest seroprevalence (41%), followed by HPV-38 and HPV-8 (both 33%). Over 90% of people retained their baseline serostatus during the 4½ year follow-up. Highest serostability was observed for HPV-88 (99.7% stayed seropositive or seronegative), while HPV-65 was least stable with 17% altering their serostatus during follow-up.Seroprevalence to cutaneous HPV types are relatively stable over time, and a single measure can be used as a reasonable marker of long-term antibody status.
Journal: Virology - Volume 407, Issue 1, 10 November 2010, Pages 26–32