کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3430425 | 1594398 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A pathogenic picorna-like virus from the endoparasitoid wasp, Pteromalus puparum: Initial discovery and partial genomic characterization
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Using electron microscopy, we demonstrated the presence of a novel small RNA-containing virus in the venom apparatus of an endoparasitic wasp, Pteromalus puparum, designated as PpSRV. Morphologically, PpSRV has classical features of picorna-like viruses. It caused the development deterioration and tissue destruction of P. puparum venom apparatus. The laboratory colony of P. puparum was infectious with PpSRV at a low level. Partial genomic sequence analysis indicated that PpSRV 3â²-proximal genome was characteristically similar to most dicistroviruses containing an internal ribosome entry site (IRES) for facilitating cap-independent translation and a 3â² ORF encoding a structural protein with three major capsid polyproteins (28, 31 and 28Â kDa) and a minor one (9.6Â kDa). Phylogenetic evolution analysis of PpSRV structural protein with the counterparts of other dicistroviruses exhibited that PpSRV belonged to the Cripavirus genus and fell into same clade with Black queen cell virus (BQCV), an infectious virus to honey bee, suggesting that PpSRV might be pathogenic to P. puparum.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 138, Issues 1â2, December 2008, Pages 144-149
Journal: Virus Research - Volume 138, Issues 1â2, December 2008, Pages 144-149
نویسندگان
Jia-Ying Zhu, Gong-Yin Ye, Qi Fang, Ma-Li Wu, Cui Hu,