کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3976382 1601027 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neutron radiation therapy for advanced thyroid cancers
ترجمه فارسی عنوان
پرتودرمانی نوترون برای سرطان های پیشرفته تیروئید
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

PurposeThe aim of this study was to review institutional outcomes for advanced thyroid cancers treated with fast neutron radiation therapy (FNRT) and photon radiation therapy (RT).Methods and materialsIn all, 62 consecutive patients were analyzed. Fifty-nine had stage IV disease. Twenty-three were treated with FNRT and 39 with photon RT. Median follow-up was 14 months. The primary endpoint was overall survival (OS).ResultsThere was no significant difference in median OS between FNRT and photon RT (26 vs 16 months; P = .49). Patients with well-differentiated histologies had superior median OS with photon RT (17 vs 69 months; P = .04). There was a nonsignificant trend toward improved OS with FNRT for medullary and anaplastic histologies.ConclusionsOutcomes in this study are in line with historical results. There is an apparent detriment in OS with FNRT for well-differentiated histologies and a trend toward improved OS with medullary and anaplastic histologies that warrants further investigation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advances in Radiation Oncology - Volume 1, Issue 3, July–September 2016, Pages 148–156
نویسندگان
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