کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3977490 1257216 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparative study of dosimetry between high-dose-rate and permanent prostate implant brachytherapies in patients with prostate adenocarcinoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Comparative study of dosimetry between high-dose-rate and permanent prostate implant brachytherapies in patients with prostate adenocarcinoma
چکیده انگلیسی

PurposeTo compare the dose coverage, conformity, and homogeneity between high-dose-rate (HDR) brachytherapy and permanent prostate implant (PPI) in the treatment of prostate adenocarcinoma.Methods and materialsFrom January 2003 to August 2004, 54 patients (108 implants) underwent HDR brachytherapy of prostate cancer with iridium-192 stepping source. Of patients who underwent PPI brachytherapy with iodine-125, 72 patients were randomly selected for the purpose of dosimetric comparison. PPI preplan was done based on transrectal ultrasound study, and postplan was done using CT 1 month after implant. Dosimetric parameters of HDR were compared to that of PPI preplan and postplan.ResultsHDR brachytherapy had lower D90 (111.5% vs. 120.2%), lower V100 (97.2% vs. 99.6%), lower natural dose ratio (1.03 vs. 1.13), higher conformal index (0.69 vs. 0.62), and higher homogeneity index (0.63 vs. 0.52) than PPI preplan (all p < 0.0001). All the dosimetric parameters of PPI postplan including D90 (86.7%), V100 (82.0%), natural dose ratio (0.92), conformal index (0.53), and homogeneity index (0.42) were inferior to HDR brachytherapy (all p < 0.0001).ConclusionsHDR brachytherapy of the prostate can provide better dose coverage, conformity, and homogeneity compared to PPI.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brachytherapy - Volume 5, Issue 4, October–December 2006, Pages 251–255
نویسندگان
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