Late chest wall toxicity after MammoSite® breast brachytherapy

Fractures occurred in ribs with V37 Gy and V44 Gy each well below 33%. As long-term toxicity data accrue from APBI series, the traditional models for estimating the biologic equivalent dose may benefit from refinements that specifically address the unique radiobiologic and physical properties intrinsic to high-dose-rate brachytherapy for breast conservation therapy.