کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3978992 1257312 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Epigenetic changes in osteosarcoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Epigenetic changes in osteosarcoma
چکیده انگلیسی
Osteosarcoma is one of the most prevalent primary bone tumors. The pathogenesis and molecular development of this tumor remains elusive. The prognosis is unfavorable due to lack of effective treatment methods. Recent advances in the epigenetics have brought a profound impact on the understanding of molecular mechanisms that lead to osteosarcoma. In this review, we summarized the current literature on epigenetic changes that are thought to contribute to the carcinogenesis of osteosarcoma, and discussed the potential diagnostic and therapeutic applications as well as future areas of research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bulletin du Cancer - Volume 98, Issue 7, July 2011, Pages E62-E68
نویسندگان
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