کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3982464 | 1257728 | 2013 | 6 صفحه PDF | دانلود رایگان |
AimTo investigate and characterize the effect of age on apparent diffusion coefficient (ADC) values in the normal adult pancreas using diffusion-weighted magnetic resonance imaging (DWI).Materials and methodsFive hundred and fifty-nine adult patients without pancreatic disease, ranging from 20–81 years of age (mean 50.9 years; 436 men, 123 women), were included in this study. Breath-hold single-shot echo-planar DWI (b-values = 0, 500 s/mm2) was employed to determine the ADCs across all patients. Dependency of ADCs on age was characterized using a Spearman rank-order correlation test.ResultsAcross the age spectrum, there was no significant correlation between ADC and age (p = 0.409).ConclusionThe findings of the present study suggest that the effect of age on ADCs can be excluded from the diagnosis of pancreatic diseases and design of future studies using breath-hold single-shot DWI and ADCs (as calculated with b-values of 0 and 500 s/mm2).
Journal: Clinical Radiology - Volume 68, Issue 10, October 2013, Pages e532–e537