کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3983297 1257759 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review
چکیده انگلیسی

AimTo establish the efficacy and complications associated with vertebroplasty in spinal metastases and myeloma.Materials and methodsA literature search was performed from inception to April 2010. Thirty relevant studies were identified. Only one was a randomized, controlled trial and seven were prospective studies. Nine hundred and eighty-seven patients aged between 45 and 72 years were included in this systematic review.ResultsMost studies report performing the procedure under local anaesthetic and continuous fluoroscopic screening, and only two centres reported treating more than four vertebrae per session. Five deaths were attributable to vertebroplasty, with a further 19 patients suffering a serious complication related to the procedure. There is some evidence to suggest that the complication rate may be related to the higher cement volume used, although the data are not robust enough for meta-analysis. Pain reduction ranged between 47–87%, similar to the results for osteoporosis. There was no correlation between pain reduction and cement volume.ConclusionThis systematic review reveals the paucity of good-quality, robust data available on the subject of percutaneous vertebroplasty in malignancy. It also highlights the apparent high risk of serious complication (2%). Further research into the subject is required in this group of patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Radiology - Volume 66, Issue 1, January 2011, Pages 63–72
نویسندگان
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