کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3983603 1257772 2010 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Diagnostic precision of CT in local staging of colon cancers: a meta-analysis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Diagnostic precision of CT in local staging of colon cancers: a meta-analysis
چکیده انگلیسی

AimTo determine the accuracy of computed tomography (CT) in detecting disease with invasion beyond the muscularis propria (MP) and malignant lymph nodes.Materials and methodsA literature search of Ovid, Embase, the Cochrane database, and Medline using Pubmed, Google™ Scholar and Vivisimo™ search engines was performed to identify studies reporting on the accuracy of CT to predict the staging of colonic tumours. Publication bias was demonstrated by Funnel plots. The sensitivity, specificity, and diagnostic odds ratio (DOR) were calculated using a bivariate random effects model and hierarchical summary operating curves (HSROC) were generated.ResultsNineteen studies fulfilled all the necessary inclusion criteria. The pooled sensitivity, specificity, DOR for detection of tumour invasion were 86% (95% CI: 78–92%); 78% (95% CI: 71–84%); 22.4 (95% CI: 11.9–42.4). Similarly, the values for nodal detection were 70% (95% CI: 63–73%); 78% (95% CI: 73–82%); 8.1(95% CI: 4.7–14.1). In the subgroup analysis, the best results were obtained in studies utilizing multidetector CT (MDCT).ConclusionPreoperative staging CT accurately distinguishes between tumours confined to the bowel wall and those invading beyond the MP; however, it is significantly poorer at identifying nodal status. MDCT provides the best results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Radiology - Volume 65, Issue 9, September 2010, Pages 708–719
نویسندگان
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