کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3987936 1601471 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A population-based study of radiotherapy in a cohort of patients with rectal cancer diagnosed between 1996 and 2000
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
A population-based study of radiotherapy in a cohort of patients with rectal cancer diagnosed between 1996 and 2000
چکیده انگلیسی

AimsTo study, in a population-based setting, the use of delayed radiotherapy (RT) in a cohort of 2008 unselected rectal cancer patients diagnosed between 1996 and 2000.Patients and methodsRadiation within 6 months of diagnosis was considered part of the primary treatment (PRT). RT given 6 months or later after diagnosis or after PRT was considered as delayed or secondary RT (SRT). Number, percentage and cumulative proportion of patients receiving SRT were calculated. The odds for receiving SRT (total and for recurrent rectal cancer only) were studied by logistic regression analysis, taking into account age, gender, co-morbidity, socio-economic status, stage, prior PRT and RT department (2 departments, each serving general hospitals only).ResultsForty-six percent of all newly diagnosed patients received RT. Ten percent (n = 203) received at least once SRT, either after PRT or as first RT, of which 96 patients for a relapsed rectal tumour (31 after PRT on the rectal tumour, 65 as a first radiation treatment). In a multivariate analysis of patients with rectal recurrence secondary pelvic irradiation was less often given after primary irradiation (OR: 0.7, 95% CI: 0.4–1.1). Patients with a stage III significantly more often received SRT on a recurrence (OR = 2.5, 95% CI = 1.4–4.5). Generally, patients in the eastern department received more often PRT and less often SRT for recurrence (OR: 0.5, 95% CI: 0.3–0.8).ConclusionsFive percent of all patients with rectal cancer received SRT on a recurrent tumour, with a large variation between the two RT departments in the region.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology (EJSO) - Volume 33, Issue 8, October 2007, Pages 993–997
نویسندگان
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