کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3988539 1601490 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prediction of the risk of hepatic failure in patients with portal vein invasion hepatoma after hepatic resection
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Prediction of the risk of hepatic failure in patients with portal vein invasion hepatoma after hepatic resection
چکیده انگلیسی

AimHepatic failure can develop after curative hepatectomy in patients with a hepatocellular carcinoma (HCC) invading the portal vein, because of cirrhosis and excessive tissue loss. This study aimed to identify the risk factors for hepatic failure in such patients.MethodForty patients with an HCC invading the portal vein underwent curative hepatectomy from January 1995 to June 2003. Eight patients developed hepatic failure and died within 3 months. Possible risk factors for this were analysed using univariate and multivariate regression. These included the liver function index, surgical blood loss, tumour pattern, portal hypertension, estimated residual liver volume measured by computed tomography (ERLVCT) and estimated residual liver volume using the indocyanine green (ICG) retention rate at 15 min (ERLVICG15).ResultsThe ERLVCT smaller than the ERLVICG15 and presence of portal hypertension were independent risk factors for post-hepatectomy hepatic failure.ConclusionHaving portal vein invasion HCC with portal hypertension or an ERLVCT less than an ERLVICG15 are significant predictors of post-hepatectomy hepatic failure. These factors are important considerations for patients with portal vein invasion HCC who could undergo curative hepatic resection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology (EJSO) - Volume 32, Issue 1, February 2006, Pages 72–76
نویسندگان
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