کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3992139 1258799 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical Impact of High-Throughput Gene Expression Studies in Lung Cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Clinical Impact of High-Throughput Gene Expression Studies in Lung Cancer
چکیده انگلیسی

:Lung cancer is the leading cause of cancer death in the United States and the world. The high mortality rate results, in part, from the lack of effective tools for early detection and the inability to identify subsets of patients who would benefit from adjuvant chemotherapy or targeted therapies. The development of high-throughput genome-wide technologies for measuring gene expression, such as microarrays, have the potential to impact the mortality rate of lung cancer patients by improving diagnosis, prognosis, and treatment. This review will highlight recent studies using high-throughput gene expression technologies that have led to clinically relevant insights into lung cancer. The hope is that diagnostic and prognostic biomarkers that have been developed as part of this work will soon be ready for wide-spread clinical application and will have a dramatic impact on the evaluation of patients with suspect lung cancer, leading to effective personalized treatment regimens.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Thoracic Oncology - Volume 4, Issue 1, January 2009, Pages 109–118
نویسندگان
, , ,