Consolidating duodenal and small bowel toxicity data via isoeffective dose calculations based on compiled clinical data

MLQ-based isoeffective calculations of dose-response data corresponding to grade ≥ 2 duodenum toxicity were found to be consistent with one another within the calculation uncertainty. The (DMLQED2,v) data could be used to determine duodenum and small bowel dose-volume constraints for new dose escalation strategies.