کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3997898 1259182 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparison of 18FDG PET-CT and bone scintigraphy for detection of bone metastases in breast cancer patients. A meta-analysis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Comparison of 18FDG PET-CT and bone scintigraphy for detection of bone metastases in breast cancer patients. A meta-analysis
چکیده انگلیسی

BackgroundWe performed a meta-analysis to compare the accuracy of 18FDG PET-CT and bone scintigraphy for the detection of bone metastases in breast cancer patients.MethodsStudies about 18FDG PET-CT and bone scintigraphy for the detection of bone metastases in breast cancer patients were systematically searched in the MEDLINE and EMBASE databases. We calculated sensitivities, specificities, diagnostic odds ratios, and likelihood ratios, and constructed summary receiver operating characteristic curves using bivariate regression models for 18FDG PET-CT and bone scintigraphy, respectively.ResultsAcross 7 studies (668 patients), sensitivity and specificity of PET-CT 0.93 (95% confidence interval [CI] = 0.82–0.98) and 0.99 (95% CI = 0.95–1.00), and of bone scintigraphy were 0.81 (95% CI = 0.58–0.93) and 0.96 (95%CI = 0.76–1.00), respectively. Area under curves for PET-CT and bone scintigraphy was 0.98 (95% CI = 0.98–1.00) and 0.94 (95% CI = 0.92–0.96), respectively.ConclusionsCompared with bone scintigraphy, 18FDG PET-CT may higher sensitivity and accuracy for detection of bone metastases in breast cancer patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Oncology - Volume 22, Issue 2, June 2013, Pages 86–91
نویسندگان
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