کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3998039 1259189 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of sternotomy as treatment option for the resection of bilateral pulmonary metastases in pediatric solid tumors
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Analysis of sternotomy as treatment option for the resection of bilateral pulmonary metastases in pediatric solid tumors
چکیده انگلیسی

BackgroundRadical surgical resection of metastases is an important prognostic factor for survival of patients suffering from solid pediatric tumors. The aim of this study is to evaluate the efficacy of median sternotomy as treatment option for the resection of multiple bilateral lung metastases in children with different tumor entities. Furthermore, the sensitivity of preoperative imaging (CT) was assessed by intraoperative findings.Patients and methodsBetween 2002 and 2007, 13 children (4 with sarcoma, 4 with nephroblastoma, 5 with hepatoblastoma) underwent median sternotomy for resection of bilateral lung metastases after R0—resection of the primary tumor. In 6/13 cases, the sternotomy was combined with the primary tumor resection.ResultsMedian patient age at the first operation was 5 years (range: 11 months to 17 years). The median total number of resected metastases per operation was 9 and ranged from 0 to 65. In 13/16 operations, the intraoperative number of metastases did not agree with the preoperative radiological work-up. Median hospital stay was 14 days (range from 9 to 36 days). Ten out of 13 children are alive after a median follow-up of 13 months (range from 6 to 66 months).ConclusionMedian sternotomy is an adequate treatment modality for the resection of bilateral pulmonary metastases as a one-stage procedure. The combination of primary tumor resection with sternotomy should be considered as a treatment option. Complete resection of metastases of solid pediatric tumors should be aimed for in order to increase the survival of these patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Oncology - Volume 17, Issue 4, December 2008, Pages 323–330
نویسندگان
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