A Free-response Evaluation Determining Value in the Computed Tomography Attenuation Correction Image for Revealing Pulmonary Incidental Findings

Protocol variations for CT-based attenuation correction (AC) in SPECT/CT imaging have a measurable impact on lesion-detection performance. The results imply that z-axis resolution and matrix size had the greatest impact on lesion detection, with a weaker but detectable dependence on the product of milliamp and seconds.