Automatic Segmentation of Cerebrospinal Fluid, White and Gray Matter in Unenhanced Computed Tomography Images

The algorithm automatically identifies CSF, WM, and GM on unenhanced CT images with high accuracy, is robust to data from different scanners, does not require any parameter setting, and takes about 5 minutes in MATLAB to process a 512 × 512 × 30 scan. The algorithm has potential use in research and clinical applications.