Volumetric Xenon-CT Imaging of Conventional and High-frequency Oscillatory Ventilation1

High-resolution volumetric ventilation maps of the lung may be obtained with the 256-slice multidetector computed tomographic scanner. There is a marked difference in the distribution of regional ventilation between CV and HFOV, with a significant gravitational ventilation gradient in CV that was not present during HFOV. This technique may be useful in exploring the mechanisms by which HFOV improves gas exchange.