Registering Histologic and MR Images of Prostate for Image-based Cancer Detection

We have developed a novel method for deformable registration of histologic and MR images of the same prostate. Besides the collection of ground-truth cancer information in MR images, the method has other potential applications. An automatic, accurate registration of histologic and MR images actually builds a bridge between in vivo anatomical information and ex vivo pathologic information, which is valuable for various clinical studies.