Hyperpolarized 3He MR Imaging of the Lung: Effect of Subject Immobilization on the Occurrence of Ventilation Defects

It was found that immobilization of the subject for an extended period led to increased number of H3He ventilation defects in the dependent portions of the lung. Therefore, after a subject is positioned in the scanner, H3He MR imaging should be performed quickly to avoid the occurrence of the immobilization-induced ventilation defects and possible overestimation of disease.