Saline Chasing Technique with Dual-Syringe Injector Systems for Multi-Detector Row Computed Tomographic Angiography: Rationale, Indications, and Protocols

Computed tomography (CT) technology has significantly changed over the last two decades. The advent of multi-detector row CT (MDCT) has resulted in rapid acquisition times and improved z-axis resolution that paved the way for CT angiography. With MDCT technology, CT angiography has become more dependent upon optimal vessel opacification and, consequently, contrast administration protocols have had to evolve. We examine the use of intravenous contrast from a historical perspective and discuss the latest methodologies, such as saline chasing techniques, that optimize the contrast bolus with CT angiography.