کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4224494 1609628 2015 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prostate carcinoma: Accuracy of diagnosis and differentiation with Dynamic Contrast-Enhanced MRI and Diffusion Weighted Imaging
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
Prostate carcinoma: Accuracy of diagnosis and differentiation with Dynamic Contrast-Enhanced MRI and Diffusion Weighted Imaging
چکیده انگلیسی

BackgroundDiffusion weighted image (DWI) and dynamic contrast enhanced MR imaging (DCE-MRI) provide excellent parameters that are useful for differentiating cancer from normal tissue in prostatic cancer patients.PurposeTo define the diagnostic value of diffusion weighted image (DWI) and dynamic contrast enhanced MR imaging (DCE-MRI) and determine whether the combination of the two techniques provides higher diagnostic accuracy for prostate cancer than each technique alone.Material and methods30 patients suggested to have prostate cancer based on high PSA value underwent MRI examination including axial T2-WI, diffusion weighted image (DWI), apparent diffusion coefficient (ADC) and dynamic contrast enhanced MRI (DCE-MRI). The final diagnosis was confirmed by histopathological study of the TRUS-guided biopsies.ResultsThe sensitivity of DCE-MRI, ADC at 1.2 and ADC at 1.4 in detection of prostatic carcinoma was 100%, 84.6% and 100% respectively (P = 0.000). The highest validity for cancer prostate is DCE-MRI (Kappa = 0.93) followed by ADC at 1.4 (Kappa = 0.86) then ADC at 1.2 (Kappa = 0.79).ConclusionsDCE-MRI and DWI have high sensitivity to differentiate cancerous from non-cancerous prostatic tissue, and the combination of both techniques increase the diagnostic accuracy of prostatic cancer than each one alone.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Egyptian Journal of Radiology and Nuclear Medicine - Volume 46, Issue 4, December 2015, Pages 1193–1203
نویسندگان
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