کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4224786 | 1609736 | 2016 | 6 صفحه PDF | دانلود رایگان |
• cMWA is a safe and effective treatment for thyroid nodules.
• Ultrasound imaging allows guidance during microwave ablation.
• Pain level during cMWA treatment is reduced in comparison to RFA.
ObjectiveTo evaluate if internally cooled microwave ablation (cMWA) is a safe and effective method for treatment of benign and malign thyroid nodules.Methods9 patients with 11 symptomatic cold benign thyroid nodules and 1 recurrent thyroid carcinoma ranging in volume from 9.1 to 197 ml (mean size 52 ± 57 ml) were treated with cMWA. The mean age of the patients was 59 years. Pain during the treatment was measured on a 10-point scale. Side effects revealed by ultrasound or patients’ complaints were documented. Periablative efficacy was measured 24 h after cMWA as change (Δ) in serum thyreoglobulin (Tg). Nodule elasticity was measured on a 4-point scale, blood circulation and echogenicity on a 3-point scale.ResultsAll patients tolerated cMWA well. Median pain intensity averaged 2.1 ± 0.8 (range: 1–3). Postablative hematoma was observed in all cases. In no cases ablation led to hoarseness, superficial burns, nodule ruptures, vagal reactions or dysphagia. cMWA lead to a significant decrease of blood circulation, nodule echogenicity and a significant increase of elasticity (Δ = 1.1 ± 0.33; 0.8 ± 0.4 and 1.1 ± 0.6 points)(p < 0.05). An average increase of 4495 ng/ml Tg was measured (p < 0.05).ConclusionscMWA is an effective and secure method for treatment of thyroid nodules.
Journal: European Journal of Radiology - Volume 85, Issue 11, November 2016, Pages 2127–2132