کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4224832 1609741 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synovitis assessed on static and dynamic contrast-enhanced magnetic resonance imaging and its association with pain in knee osteoarthritis: A cross-sectional study
ترجمه فارسی عنوان
سینووییت بر روی تصویربرداری رزونانس مغناطیسی با کنتراست ثابت و پویا و ارتباط آن با درد در استئوآرتریت زانو ارزیابی شد: یک مطالعه مقطعی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
چکیده انگلیسی

ObjectivesTo investigate the association between pain and peripatellar-synovitis on static and dynamic contrast-enhanced MRI in knee osteoarthritis.MethodsIn a cross-sectional setting, knee synovitis was assessed using 3-Tesla MRI and correlated with pain using the knee injury and osteoarthritis outcome score (KOOS). Synovitis was assessed in the peripatellar recesses with: (i) dynamic contrast-enhanced (DCE)-MRI, using both pharmacokinetic and heuristic models, (ii) contrast-enhanced (CE)-MRI, and (iii) non-CE-MRI. The DCE-MRI variable IRExNvoxel was chosen as the primary variable in the analyses.ResultsValid data were available in 94 persons with a mean age of 65 years, a BMI of 32.3 kg/m2 and a mean Kellgren-Lawrence grade of 2.5. IRExNvoxel showed a statically significant correlation with KOOS-Pain (r = −0.34; p = 0.001), as was the case with all DCE-variables but one. Correlations between static MRI-variables and KOOS-Pain ranged between −0.21 < r < −0.29 (p < 0.040). Intraclass correlation coefficients ranged between 0.90-0.99 for the heuristic and 0.66-0.93 for the pharmacokinetic DCE-MRI variables.ConclusionsThe results confirm an association between peripatellar-synovitis and pain in KOA. Overall, DCE-MRI showed stronger correlations with KOOS-Pain compared to static MRI. DCE-MRI analyses were highly reproducible and have the potential to be used to further investigate the role of inflammation and perfusion in KOA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 85, Issue 6, June 2016, Pages 1099–1108
نویسندگان
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