کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4225070 | 1609745 | 2016 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Hybrid imaging of the bowel using PET/MR enterography: Feasibility and first results Hybrid imaging of the bowel using PET/MR enterography: Feasibility and first results](/preview/png/4225070.png)
PurposeTo implement a protocol for PET/MR enterography for a multimodal assessment of intestinal pathologies.Materials and Methods19 patients with bowel malignancies, Crohn’s disease or fever of unknown origin (male: n = 14, female: n = 5, age: 57 ± 13 years) underwent PET/MR enterography with either [18F]FDG (n = 10) or [68Ga]-DOTATOC (n = 9) using an integrated scanner. For small bowel distension a contrast solution (1500 cm3 of mannitol and locust bean gum) was ingested. The following sequences were acquired: (a) coronal TrueFISP; (b) coronal T2w HASTE; (c) coronal dynamic T1w VIBE; (d) axial and coronal T1w FLASH post gadolinium. All datasets were reviewed by two readers with regard to co-registration of anatomical structures based on a 3-point ordinal scale as well as overall image quality using a 4-point ordinal scale. Furthermore, visualization of intestinal and extra-intestinal pathologies was assessed.ResultsPET/MR enterography was well tolerated by all patients. High overall MR image quality was achieved (mean score: 3.2 ± 0.6) with good co-registration of PET and MRI (mean scores: 2.6 to 3.0). PET/MR enterography allowed for an excellent visualization of both intestinal as well as extra-intestinal pathologies.ConclusionPET/MR enterography is technically feasible and offers good co-registration of bowel structures. This novel method enables a multimodal assessment of bowel lesions in malignant and inflammatory disease.
Journal: European Journal of Radiology - Volume 85, Issue 2, February 2016, Pages 414–421