کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4225074 | 1609745 | 2016 | 8 صفحه PDF | دانلود رایگان |
• DCE-MRI is used for breast cancer screening of women at increased risk.
• Breast cancer is sometimes overlooked or misinterpreted in screening with MRI.
• A computer-aided detection system can automatically detect breast cancers missed in MRI.
PurposeTo evaluate the performance of an automated computer-aided detection (CAD) system to detect breast cancers that were overlooked or misinterpreted in a breast MRI screening program for women at increased risk.MethodsWe identified 40 patients that were diagnosed with breast cancer in MRI and had a prior MRI examination reported as negative available. In these prior examinations, 24 lesions could retrospectively be identified by two breast radiologists in consensus: 11 were scored as visible and 13 as minimally visible. Additionally, 120 normal scans were collected from 120 women without history of breast cancer or breast surgery participating in the same MRI screening program. A fully automated CAD system was applied to this dataset to detect malignant lesions.ResultsAt 4 false-positives per normal case, the sensitivity for the detection of cancer lesions that were visible or minimally visible in retrospect in prior-negative examinations was 0.71 (95% CI = 0.38–1.00) and 0.31 (0.07–0.59), respectively.ConclusionsA substantial proportion of cancers that were misinterpreted or overlooked in an MRI screening program was detected by a CAD system in prior-negative examinations. It has to be clarified with further studies if such a CAD system has an influence on the number of misinterpreted and overlooked cancers in clinical practice when results are given to a radiologist.
Journal: European Journal of Radiology - Volume 85, Issue 2, February 2016, Pages 472–479