Usefulness of free-breathing readout-segmented echo-planar imaging (RESOLVE) for detection of malignant liver tumors: Comparison with single-shot echo-planar imaging (SS-EPI)

• A prospective study revealed the usefulness of RESOLVE for detecting malignant liver tumor.
• The scanning time of RESOLVE was shorter than that of respiratory-triggered SS-EPI.
• RESOLVE minimized susceptibility artifact in the right lobe of the liver.
• RESOLVE provides a comparable detectability of malignant liver tumor compared with SS-EPI.

PurposeWe aimed to clarify the usefulness of free-breathing readout-segmented echo-planar imaging (RESOLVE), which is multi-shot echo-planar imaging based on a 2D-navigator-based reacquisition technique, for detecting malignant liver tumor.Materials and methodsIn 77 patients with malignant liver tumors, free-breathing RESOLVE and respiratory-triggered single-shot echo-planar imaging (SS-EPI) at 3-T MR unit were performed. We set a scan time up to approximately 5 min (300 s) before examination, measured actual scan time and assessed (1) susceptibility and (2) motion artifacts in the right and left liver lobes (3, no artifact; 1, marked), and (3) detectability of malignant liver tumors (3, good; 1, poor) using a 3-point scale.ResultsThe median actual scan time of RESOLVE/SS-EPI was 365/423 s. The median scores of each factor in RESOLVE/SS-EPI were as following in this order: (1) 3/2 (right lobe); 3/3 (left lobe), (2) 2/3 (right lobe); 1/2 (left lobe), and (3) 3/3, respectively. Significant differences were noted between RESOLVE and SS-EPI in all evaluated factors (P < 0.05) except for susceptibility of left lobe and detectability of the lesions.ConclusionDespite the effect of motion artifacts, RESOLVE provides a comparable detectability of the lesion and the advantage of reducing scanning time compared with SS-EPI.